Preparations containing metal ions (antacids, preparations containing iron, magnesium, calcium) form inactive chelates with tetracycline, and therefore it is necessary to avoid their simultaneous administration.
Tetracycline tablets are prescribed for etiotropic therapy of pathologies of infectious and inflammatory origin, the development of which is caused by the multiplication of pathogens sensitive to the main component of the drug. Typically, the drug is used in the treatment of: pneumonia - an infectious pneumonia; acne complicated by infectious inflammation; pleural empyema - accumulations of pus inside the pleural cavity; osteomyelitis - purulent lesions of bone tissue having different localization; bronchitis - infectious inflammation of the bronchi; a variety of intestinal infections; cholecystitis - lesions of the gallbladder; conjunctivitis - inflammation of the conjunctiva; pyelonephritis - purulent-inflammatory processes in the pyelocaliceal system of the kidneys; blepharitis - infectious and inflammatory processes on the eyelids; endometritis - inflammation of the uterine mucosa; brucellosis - a specific form of infection that is transmitted from certain animal species; endocarditis - an infectious process that occurs on the surface of the mucous membranes in the myocardial cavities; gonorrhea - a genital infection characterized by purulent lesions of the lower urinary tract; prostatitis - inflammation of the prostate in the stronger sex; syphilis - an infection that is transmitted through sexual contact.
Along with this, the drug is prescribed for the prevention of the development of infectious complications after surgery.
Side effects From the nervous system and sensory organs: increased intracranial pressure, dizziness or instability. From the cardiovascular system and blood (hematopoiesis, hemostasis): hemolytic anemia, thrombocytopenia, neutropenia. From the gastrointestinal tract: loss of appetite, nausea, vomiting, diarrhea, glossitis, esophagitis, gastritis, ulceration of the stomach and duodenum, hypertrophy of the papillae of the tongue, dysphagia, hepatotoxic effect, increased activity of hepatic transaminases, hyperbilirubinemia, pancreatic benignitis, anti-tuberculosis, antibiotics. From the genitourinary system: nephrotoxic effect, azotemia, hypercreatininemia. Allergic reactions: maculopapular rash, flushing of the skin, angioedema, anaphylactoid reactions, drug systemic lupus erythematosus.
Other: photosensitization, violation of the formation of bone and dental tissue, discoloration of tooth enamel in children, superinfection, candidiasis, hypovitaminosis B.