A common question that often comes to mind is whether clinical trials are required to be conducted locally as a stated or implicit condition to obtain marketing approval. The majority of countries, including India, require clinical trials to be conducted locally as a pre-condition for obtaining marketing approval. It is done to prove the safety and efficacy of a drug or medical device that satisfies the definition of a new drug and investigational medical device, respectively. Learn Clinical Research Courses.\nHowever, if the investigational medical device has been imported from the United States of America, the United Kingdom, Australia, Japan, Canada, or the European Union, then the requirement to conduct a clinical trial locally can be waived off if a free sale certificate is obtained and submitted from the relevant jurisdiction. Take Clinical Research Training.