Irrespective of where the sponsors are incorporated, clinical trial sponsors can directly fund a clinical trial. The sponsors are responsible for choosing a team of investigators and a physical investigator who then leads the team of investigators. The sponsor of a clinical trial can directly pay the investigators for their services. The sponsor is also permitted to make payments for the site, also selected by the sponsor, for the clinical trial for providing in-patient facilities, among various others. In case of investigators being the site employees, the sponsor can make direct payments to the site, which is later redistributed to the investigators. Learn Clinical Research Courses.