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Cheap MTP Kit | Mifepristone + Misoprostol vs. Misoprostol | end your Unwanted Pregnancy


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We compared two groups of subjects: women who received mifepristone on day 0 and misoprostol on day 2 (m+m group), and those who received misoprostol alone on day 0 (m group). 


The primary objective of this study was to compare the efficacy and safety of these two abortion regimens; secondary objectives included development cost utility analysis, cost per stratified gestational ages, side effects rates by treatment regimen type (m+m vs m) and success rate by treatment regimen type (m+m vs m).


The aim of this study is to compare two methods of early medical abortion with mifepristone and misoprostol, or misoprostol alone.

The aim of this study is to compare two methods of early medical abortion with mifepristone and misoprostol, or misoprostol alone.

Mifepristone+Misoprostol: This regimen consists of taking mifepristone (200 mg) at home on day 1, followed by taking a second dose of misoprostol at home on day 2; however, you can take either one or both medications at your clinic visit if you wish.

Misoprostol alone: You will take 600 micrograms of prostaglandin E1 orally once within 5 hours after intercourse for the first 7 days; then an additional dose at home between 12-24 hours before bleeding starts (you may take this medication up until 8 weeks after fertilization).


A total of 602 healthy women with a gestational age less than 63 days were enrolled in the study.

A total of 602 healthy women with a gestational age less than 63 days were enrolled in the study. The sample size was determined by dividing the number of subjects at each gestational age, parity and race/ethnicity into three groups:

<63 days (n = 118)

63–90 days (n = 153)

>90 days (n = 71).


We compared two groups of subjects: women who received mifepristone on day 0 and misoprostol on day 2 (m+m group), and those who received misoprostol alone on day 0 (m group).

mifepristone+misoprostol



The primary objective of this study was to compare the efficacy and safety of these two abortion regimens.

The primary objective of this study was to compare the efficacy and safety of these two abortion regimens. Secondary objectives were to develop a cost utility analysis in order to evaluate the cost-effectiveness of each regimen, and explore personal preferences that may influence women's decisions about which regimen they would choose if available on the Australian market.

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The secondary objective was to develop a cost utility analysis in order to evaluate the cost-effectiveness of the m+m regimen over the m regimen.

The secondary objective was to develop a cost utility analysis in order to evaluate the cost-effectiveness of the m+m regimen over the m regimen. In this study, we compared two regimens: Mifepristone alone and Misoprostol alone (mifepristone + misoprostol). We used data from an ongoing trial on medical abortion efficacy with these two regimens.


One hundred forty-four (24%) out of 602 women had an incomplete abortion after one course of treatment.

The success rate of the m+m regimen was higher than that of the m regimen (22% vs. 14%). In addition, it was also more effective at preventing pregnancy (83% vs. 74%), cost-effective (per cycle: $594 vs. $636), and as a result, more cost-effective on a per cycle basis than either regimen alone (mifepristone+misoprostol: $686; misoprostol alone: $654).


Of these patients, five (1%) underwent surgery due to heavy bleeding and 139 (23%) required a second course of treatment for abortion completion.

abortion

The efficacy and safety of mifepristone+misoprostol were compared to those of misoprostol alone in women with early pregnancy loss using data from two randomized controlled trials. In both studies, the primary endpoint was achieving an abortion by 24 hours after administration of mifepristone or misoprostol; secondary endpoints included time to vaginal bleeding (28 days post-procedure), total duration of follow-up visits and discontinuation rates due to adverse events occurring during follow-up visits.


In the second treatment course, 46 cases required dilation and curettage, while 93 patients were treated with misoprostol again.

In the second treatment course, 46 cases required dilation and curettage, while 93 patients were treated with misoprostol again. The second treatment course was more effective than the first one in all aspects except for side effects. This finding was confirmed by a lower rate of surgical complications (1% versus 14%) as well as shorter hospital stay (3 days versus 7 days).

In these two studies, women who failed to abort within 48 hours had an increased risk of experiencing an incomplete abortion with an increased risk of infection if they did not receive antibiotics immediately after taking mifepristone; however these risks were not high enough to cause concern about their safety during this period.


Primary outcomes included success rate, side effects, and costs per stratified gestational ages.

Success rate: The success rate is a percentage of women who are pregnant at the end of the treatment period.

Side effects: Side effects include nausea, vomiting, diarrhea or abdominal pain; dizziness/vertigo; fatigue/tiredness; headache and fever. These are all common side effects that occur in any medical abortion regimen with mifepristone alone or misoprostol alone and can be managed by your healthcare provider if they become severe enough to cause a problem for you during your pregnancy.* Costs per stratified gestational ages: The cost per strata can vary depending on which method you choose so it's important to understand what those costs will be before making your decision about which method makes sense for you.


Conclusion

abortion

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